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Structural basis for the interaction between the first SURP domain of the SF3A1 subunit in U2 snRNP and the human splicing factor SF1

SURP domains are exclusively found in splicing‐related proteins in all eukaryotes. SF3A1, a component of the U2 snRNP, has two tandem SURP domains, SURP1, and SURP2. SURP2 is permanently associated with a specific short region of SF3A3 within the SF3A protein complex whereas, SURP1 binds to the spli...

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Detalles Bibliográficos
Autores principales: Nameki, Nobukazu, Takizawa, Masayuki, Suzuki, Takayuki, Tani, Shoko, Kobayashi, Naohiro, Sakamoto, Taiichi, Muto, Yutaka, Kuwasako, Kanako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514218/
https://www.ncbi.nlm.nih.gov/pubmed/36173164
http://dx.doi.org/10.1002/pro.4437