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Flow pattern–dependent mitochondrial dynamics regulates the metabolic profile and inflammatory state of endothelial cells

Endothelial mitochondria play a pivotal role in maintaining endothelial cell (EC) homeostasis through constantly altering their size, shape, and intracellular localization. Studies show that the disruption of the basal mitochondrial network in EC, forming excess fragmented mitochondria, implicates c...

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Detalles Bibliográficos
Autores principales: Hong, Soon-Gook, Shin, Junchul, Choi, Soo Young, Powers, Jeffery C., Meister, Benjamin M., Sayoc, Jacqueline, Son, Jun Seok, Tierney, Ryan, Recchia, Fabio A., Brown, Michael D., Yang, Xiaofeng, Park, Joon-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514384/
https://www.ncbi.nlm.nih.gov/pubmed/36134656
http://dx.doi.org/10.1172/jci.insight.159286