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Activation of uroepithelial 5-HT(4)R inhibits mechanosensory activity of murine bladder afferent nerves

Serotonin (5-HT) is known to act via multiple 5-HT receptors at spinal and supraspinal levels to regulate micturition. However, the contribution of peripheral 5-HT and its receptors in bladder physiology and pathology is not very well understood, despite evidence showing expression of multiple 5-HT...

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Detalles Bibliográficos
Autores principales: Lu, Yu, Li, Jie, Dong, Li, Luo, Ping, Zhang, Guohua, Rong, Weifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514655/
https://www.ncbi.nlm.nih.gov/pubmed/36176773
http://dx.doi.org/10.3389/fphys.2022.990178