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H3K9me1/2 methylation limits the lifespan of daf-2 mutants in C. elegans

Histone methylation plays crucial roles in the development, gene regulation, and maintenance of stem cell pluripotency in mammals. Recent work shows that histone methylation is associated with aging, yet the underlying mechanism remains unclear. In this work, we identified a class of putative histon...

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Detalles Bibliográficos
Autores principales: Huang, Meng, Hong, Minjie, Hou, Xinhao, Zhu, Chengming, Chen, Di, Chen, Xiangyang, Guang, Shouhong, Feng, Xuezhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514849/
https://www.ncbi.nlm.nih.gov/pubmed/36125117
http://dx.doi.org/10.7554/eLife.74812