Loss of full-length dystrophin expression results in major cell-autonomous abnormalities in proliferating myoblasts

Duchenne muscular dystrophy (DMD) affects myofibers and muscle stem cells, causing progressive muscle degeneration and repair defects. It was unknown whether dystrophic myoblasts—the effector cells of muscle growth and regeneration—are affected. Using transcriptomic, genome-scale metabolic modelling...

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Detalles Bibliográficos
Autores principales: Gosselin, Maxime RF, Mournetas, Virginie, Borczyk, Malgorzata, Verma, Suraj, Occhipinti, Annalisa, Róg, Justyna, Bozycki, Lukasz, Korostynski, Michal, Robson, Samuel C, Angione, Claudio, Pinset, Christian, Gorecki, Dariusz C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514850/
https://www.ncbi.nlm.nih.gov/pubmed/36164827
http://dx.doi.org/10.7554/eLife.75521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514850/
https://www.ncbi.nlm.nih.gov/pubmed/36164827
http://dx.doi.org/10.7554/eLife.75521

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