Effect of the BMPR-II-SMAD3/MRTF pathway on proliferation and migration of ASMCs and the mechanism in asthma

BACKGROUND: A variety of smooth muscle-specific genes and proteins, including SMAD3, BMPR-II, and MRTF, are involved in airway remodeling in asthma. As a receptor of bone morphogenetic protein (BMP) signaling, BMPR-II has important roles in airway remodeling in asthma. However, the underlying mechan...

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Detalles Bibliográficos
Autores principales: Gu, Wenbo, Lei, Jiahui, Zhu, He, Xiao, Yali, Zhang, Zhenping, Zhao, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515032/
https://www.ncbi.nlm.nih.gov/pubmed/36008606
http://dx.doi.org/10.1007/s11033-022-07764-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515032/
https://www.ncbi.nlm.nih.gov/pubmed/36008606
http://dx.doi.org/10.1007/s11033-022-07764-9

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