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A new era for oral peptides: SNAC and the development of oral semaglutide for the treatment of type 2 diabetes

Glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) were first introduced for the treatment of type 2 diabetes (T2D) in 2005. Despite the high efficacy and other benefits of GLP-1RAs, their uptake was initially limited by the fact that they could only be administered by injection. Semagluti...

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Detalles Bibliográficos
Autores principales: Aroda, Vanita R., Blonde, Lawrence, Pratley, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515042/
https://www.ncbi.nlm.nih.gov/pubmed/35838946
http://dx.doi.org/10.1007/s11154-022-09735-8