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Blood–brain barrier opening in a large animal model using closed-loop microbubble cavitation-based feedback control of focused ultrasound sonication

Focused ultrasound (FUS) in combination with microbubbles has been established as a promising technique for noninvasive and localized Blood–brain barrier (BBB) opening. Real-time passive cavitation detection (PCD)-based feedback control of the FUS sonication is critical to ensure effective BBB openi...

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Detalles Bibliográficos
Autores principales: Chien, Chih-Yen, Xu, Lu, Pacia, Christopher Pham, Yue, Yimei, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515082/
https://www.ncbi.nlm.nih.gov/pubmed/36167747
http://dx.doi.org/10.1038/s41598-022-20568-y