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Polymorphisms in Schizophrenia-Related Genes Are Potential Predictors of Antipsychotic Treatment Resistance and Refractoriness

BACKGROUND: Approximately 30% of individuals with schizophrenia (SZ) are resistant to conventional antipsychotic drug therapy (AP). Of these, one-third are also resistant to the second-line treatment, clozapine. Treatment resistance and refractoriness are associated with increased morbidity and disa...

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Detalles Bibliográficos
Autores principales: Zazueta, Alejandra, Castillo, Tito, Cavieres, Álvaro, González, René, Abarca, Maximiliano, Nieto, Rodrigo R, Deneken, Javier, Araneda, Cristian, Moya, Pablo R, Bustamante, M Leonor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515128/
https://www.ncbi.nlm.nih.gov/pubmed/35416253
http://dx.doi.org/10.1093/ijnp/pyac025