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Polymorphisms in Schizophrenia-Related Genes Are Potential Predictors of Antipsychotic Treatment Resistance and Refractoriness
BACKGROUND: Approximately 30% of individuals with schizophrenia (SZ) are resistant to conventional antipsychotic drug therapy (AP). Of these, one-third are also resistant to the second-line treatment, clozapine. Treatment resistance and refractoriness are associated with increased morbidity and disa...
Autores principales: | Zazueta, Alejandra, Castillo, Tito, Cavieres, Álvaro, González, René, Abarca, Maximiliano, Nieto, Rodrigo R, Deneken, Javier, Araneda, Cristian, Moya, Pablo R, Bustamante, M Leonor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515128/ https://www.ncbi.nlm.nih.gov/pubmed/35416253 http://dx.doi.org/10.1093/ijnp/pyac025 |
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