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Basolateral Amygdala SIRT1/PGC-1α Mitochondrial Biogenesis Pathway Mediates Morphine Withdrawal-Associated Anxiety in Mice

BACKGROUND: Anxiety is a negative emotion that contributes to craving and relapse during drug withdrawal. Sirtuins 1 (SIRT1) has been reported to be critical in both negative emotions and drug addiction. However, it remains incompletely elucidated whether SIRT1 is involved in morphine withdrawal-ass...

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Detalles Bibliográficos
Autores principales: Yin, Fangyuan, Zhang, Jinyu, Liu, Yige, Zhai, Yifang, Luo, Danlei, Yan, Xinyue, Feng, Yue, Lai, Jianghua, Zheng, Haibo, Wei, Shuguang, Wang, Yunpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515130/
https://www.ncbi.nlm.nih.gov/pubmed/35797010
http://dx.doi.org/10.1093/ijnp/pyac040