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5-HT(5A) Receptor Antagonist ASP5736 Ameliorates Several Abnormal Behaviors in an Fmr1-Targeted Transgenic Male Rat Model of Fragile X Syndrome

BACKGROUND: Fragile X syndrome (FXS) is a genetic condition that causes a range of developmental problems, including intellectual disability, aggressive behavior, anxiety, abnormal sensory processing, and cognitive impairment. Despite intensive preclinical research in Fmr1-targeted transgenic mice,...

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Detalles Bibliográficos
Autores principales: Yamazaki, Mayako, Arai, Takatomo, Yarimizu, Junko, Matsumoto, Mitsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515134/
https://www.ncbi.nlm.nih.gov/pubmed/35882205
http://dx.doi.org/10.1093/ijnp/pyac041