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The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction

Dystrophin is the central protein of the dystrophin-glycoprotein complex (DGC) in skeletal and heart muscle cells. Dystrophin connects the actin cytoskeleton to the extracellular matrix (ECM). Severing the link between the ECM and the intracellular cytoskeleton has a devastating impact on the homeos...

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Detalles Bibliográficos
Autores principales: Wilson, Darren Graham Samuel, Tinker, Andrew, Iskratsch, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515174/
https://www.ncbi.nlm.nih.gov/pubmed/36168044
http://dx.doi.org/10.1038/s42003-022-03980-y