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HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway

Homeobox A5 (HOXA5) is a transcription factor in mammalian and can regulate cell differentiation, proliferation, and apoptosis as well as tumorigenesis. However, little is known on whether and how HOXA5 can regulate the malignant behaviors of cholangiocarcinoma. The methylation levels of HOXA5 were...

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Detalles Bibliográficos
Autores principales: Xiong, Fei, Liu, Wenzheng, Wang, Xin, Wu, Guanhua, Wang, Qi, Guo, Tong, Huang, Wenhua, Wang, Bing, Chen, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515223/
https://www.ncbi.nlm.nih.gov/pubmed/36167790
http://dx.doi.org/10.1038/s41419-022-05279-6