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Quality control of [(177)Lu]Lu-PSMA preparations using HPLC: effect of sample composition and ligand on recovery

BACKGROUND: [(177)Lu]Lu-PSMA is used for the treatment of metastatic castration-resistant prostate cancer. For in-house productions, quality control methods are essential for ensuring product quality, and thus patient safety. During HPLC method development for quality control of [(177)Lu]Lu-PSMA-I&a...

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Detalles Bibliográficos
Autores principales: Aalbersberg, Else A., Cao, Tammie T., Geluk-Jonker, Martine M., Hendrikx, Jeroen J. M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515298/
https://www.ncbi.nlm.nih.gov/pubmed/36166155
http://dx.doi.org/10.1186/s41181-022-00178-9