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A survey of protein interactions and posttranslational modifications that influence the polyglutamine diseases

The presence and aggregation of misfolded proteins has deleterious effects in the nervous system. Among the various diseases caused by misfolded proteins is the family of the polyglutamine (polyQ) disorders. This family comprises nine members, all stemming from the same mutation—the abnormal elongat...

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Detalles Bibliográficos
Autores principales: Johnson, Sean L., Tsou, Wei-Ling, Prifti, Matthew V., Harris, Autumn L., Todi, Sokol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515312/
https://www.ncbi.nlm.nih.gov/pubmed/36187346
http://dx.doi.org/10.3389/fnmol.2022.974167