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Reduced B cell antigenicity of Omicron lowers host serologic response

The SARS-CoV-2 Omicron variant evades most neutralizing vaccine-induced antibodies and is associated with lower antibody titers upon breakthrough infections than previous variants. However, the mechanism remains unclear. Here, we find using a geometric deep-learning model that Omicron’s extensively...

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Detalles Bibliográficos
Autores principales: Tubiana, Jérôme, Xiang, Yufei, Fan, Li, Wolfson, Haim J., Chen, Kong, Schneidman-Duhovny, Dina, Shi, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515332/
https://www.ncbi.nlm.nih.gov/pubmed/36223774
http://dx.doi.org/10.1016/j.celrep.2022.111512