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Integrated analysis of bulk and single-cell RNA sequencing reveals the interaction of PKP1 and tumor-infiltrating B cells and their therapeutic potential for nasopharyngeal carcinoma

Immunotherapy is an individualized therapeutic strategy for nasopharyngeal carcinoma (NPC). However, few molecular targets are clinically satisfactory. This work aimed to integrate bulk and single-cell RNA sequencing data to identify novel biomarkers involved in NPC. We performed differentially expr...

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Detalles Bibliográficos
Autores principales: Huang, Yu-Mei, Wang, Lin-Qian, Liu, Ying, Tang, Fa-Qing, Zhang, Wen-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515358/
https://www.ncbi.nlm.nih.gov/pubmed/36186467
http://dx.doi.org/10.3389/fgene.2022.935749