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Timapiprant, a prostaglandin D2 receptor antagonist, ameliorates pathology in a rat Alzheimer’s model

We investigated the relevance of the prostaglandin D2 pathway in Alzheimer’s disease, because prostaglandin D2 is a major prostaglandin in the brain. Thus, its contribution to Alzheimer’s disease merits attention, given the known impact of the prostaglandin E2 pathway in Alzheimer’s disease. We used...

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Detalles Bibliográficos
Autores principales: Wallace, Charles H, Oliveros, Giovanni, Serrano, Peter A, Rockwell, Patricia, Xie, Lei, Figueiredo-Pereira, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515385/
https://www.ncbi.nlm.nih.gov/pubmed/36167438
http://dx.doi.org/10.26508/lsa.202201555