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Developments and challenges of FLT3 inhibitors in acute myeloid leukemia

FLT3 mutations are one of the most common genetic alterations in acute myeloid leukemia (AML) and are identified in approximately one-third of newly diagnosed patients. Aberrant FLT3 receptor signaling has important implications for the biology and clinical management of AML. In recent years, target...

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Detalles Bibliográficos
Autores principales: Ge, Shuai-Shuai, Liu, Song-Bai, Xue, Sheng-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515417/
https://www.ncbi.nlm.nih.gov/pubmed/36185253
http://dx.doi.org/10.3389/fonc.2022.996438