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Interferon-γ exposure of human iPSC-derived neurons alters major histocompatibility complex I and synapsin protein expression

Human epidemiological data links maternal immune activation (MIA) during gestation with increased risk for psychiatric disorders with a putative neurodevelopmental origin, including schizophrenia and autism. Animal models of MIA provide evidence for this association and suggest that inflammatory cyt...

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Detalles Bibliográficos
Autores principales: Pavlinek, Adam, Matuleviciute, Rugile, Sichlinger, Laura, Dutan Polit, Lucia, Armeniakos, Nikolaos, Vernon, Anthony Christopher, Srivastava, Deepak Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515429/
https://www.ncbi.nlm.nih.gov/pubmed/36186864
http://dx.doi.org/10.3389/fpsyt.2022.836217