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Interferon-γ exposure of human iPSC-derived neurons alters major histocompatibility complex I and synapsin protein expression
Human epidemiological data links maternal immune activation (MIA) during gestation with increased risk for psychiatric disorders with a putative neurodevelopmental origin, including schizophrenia and autism. Animal models of MIA provide evidence for this association and suggest that inflammatory cyt...
Autores principales: | Pavlinek, Adam, Matuleviciute, Rugile, Sichlinger, Laura, Dutan Polit, Lucia, Armeniakos, Nikolaos, Vernon, Anthony Christopher, Srivastava, Deepak Prakash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515429/ https://www.ncbi.nlm.nih.gov/pubmed/36186864 http://dx.doi.org/10.3389/fpsyt.2022.836217 |
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