Obesity-induced miR-802 directly targets AMPK and promotes nonalcoholic steatohepatitis in mice

OBJECTIVE: Obesity-associated nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver failure and death. However, the pathogenesis of NAFLD and its severe form, nonalcoholic steatohepatitis (NASH), is poorly understood. The energy sensor, AMP-activated protein kinase (AMPK), has decreas...

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Detalles Bibliográficos
Autores principales: Sun, Hao, Seok, Sunmi, Jung, Hyunkyung, Kemper, Byron, Kemper, Jongsook Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515436/
https://www.ncbi.nlm.nih.gov/pubmed/36126896
http://dx.doi.org/10.1016/j.molmet.2022.101603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515436/
https://www.ncbi.nlm.nih.gov/pubmed/36126896
http://dx.doi.org/10.1016/j.molmet.2022.101603

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