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Obesity-induced miR-802 directly targets AMPK and promotes nonalcoholic steatohepatitis in mice
OBJECTIVE: Obesity-associated nonalcoholic fatty liver disease (NAFLD) is a leading cause of liver failure and death. However, the pathogenesis of NAFLD and its severe form, nonalcoholic steatohepatitis (NASH), is poorly understood. The energy sensor, AMP-activated protein kinase (AMPK), has decreas...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515436/ https://www.ncbi.nlm.nih.gov/pubmed/36126896 http://dx.doi.org/10.1016/j.molmet.2022.101603 |