Genetic determinants of apixaban plasma levels and their relationship to bleeding and thromboembolic events

Apixaban is a direct oral anticoagulant, a factor Xa inhibitor, used for the prevention of ischemic stroke in patients with atrial fibrillation. Despite using recommended dosing a few patients might still experience bleeding or lack of efficacy that might be related to inappropriate drug exposure. W...

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Detalles Bibliográficos
Autores principales: Attelind, Sofia, Hallberg, Pär, Wadelius, Mia, Hamberg, Anna-Karin, Siegbahn, Agneta, Granger, Christopher B., Lopes, Renato D., Alexander, John H., Wallentin, Lars, Eriksson, Niclas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515473/
https://www.ncbi.nlm.nih.gov/pubmed/36186466
http://dx.doi.org/10.3389/fgene.2022.982955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515473/
https://www.ncbi.nlm.nih.gov/pubmed/36186466
http://dx.doi.org/10.3389/fgene.2022.982955

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