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DLC1 inhibits colon adenocarcinoma cell migration by promoting secretion of the neurotrophic factor MANF
DLC1 (deleted in liver cancer-1) is downregulated or deleted in colorectal cancer (CRC) tissues and functions as a potent tumor suppressor, but the underlying molecular mechanism remains elusive. We found that the conditioned medium (CM) collected from DLC1-overexpressed SW1116 cells inhibited the m...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515611/ https://www.ncbi.nlm.nih.gov/pubmed/36185184 http://dx.doi.org/10.3389/fonc.2022.900166 |