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DLC1 inhibits colon adenocarcinoma cell migration by promoting secretion of the neurotrophic factor MANF

DLC1 (deleted in liver cancer-1) is downregulated or deleted in colorectal cancer (CRC) tissues and functions as a potent tumor suppressor, but the underlying molecular mechanism remains elusive. We found that the conditioned medium (CM) collected from DLC1-overexpressed SW1116 cells inhibited the m...

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Detalles Bibliográficos
Autores principales: Chu, Yi-Min, Xu, Ying, Zou, Xiu-Qun, Zhou, Feng-Li, Deng, Yu-Liang, Han, Yu-Tong, Li, Ji, Yang, Da-Ming, Peng, Hai-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515611/
https://www.ncbi.nlm.nih.gov/pubmed/36185184
http://dx.doi.org/10.3389/fonc.2022.900166