Combinatorial suicide gene strategies for the safety of cell therapies

Gene-modified cellular therapies carry inherent risks of severe and potentially fatal adverse events, including the expansion of alloreactive cells or malignant transformation due to insertional mutagenesis. Strategies to mitigate uncontrolled proliferation of gene-modified cells include co-transfec...

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Detalles Bibliográficos
Autores principales: Falcon, Corey, Smith, Lauren, Al-Obaidi, Mustafa, Abu Zaanona, Mohammed, Purvis, Katelyn, Minagawa, Kentaro, Athar, Mohammad, Salzman, Donna, Bhatia, Ravi, Goldman, Frederick, Di Stasi, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515659/
https://www.ncbi.nlm.nih.gov/pubmed/36189285
http://dx.doi.org/10.3389/fimmu.2022.975233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515659/
https://www.ncbi.nlm.nih.gov/pubmed/36189285
http://dx.doi.org/10.3389/fimmu.2022.975233

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