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Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants

Asymmetric signalling centres in the early embryo are essential for axis formation in vertebrates. These regions (e.g. amphibian dorsal morula, mammalian anterior visceral endoderm) require stabilised nuclear β-catenin, but the role of localised Wnt ligand signalling activity in their establishment...

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Detalles Bibliográficos
Autores principales: Houston, Douglas W., Elliott, Karen L., Coppenrath, Kelsey, Wlizla, Marcin, Horb, Marko E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515810/
https://www.ncbi.nlm.nih.gov/pubmed/35946588
http://dx.doi.org/10.1242/dev.200552