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Increased seizure sensitivity in pregnant mice with genetic knockdown of acid sensing ion channel 2a is associated with impaired hippocampal inflammatory response

Acid sensing ion channels (ASICs) are mechano- and chemo-receptor channels that are activated by drops in extracellular pH as occurs after neurotransmission. In our previous study, we demonstrated that mice subjected to reduced utero-placental perfusion pressure during pregnancy, to mimic the pregna...

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Detalles Bibliográficos
Autores principales: Jones-Muhammad, Maria, Shao, Qingmei, Warrington, Junie P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9515891/
https://www.ncbi.nlm.nih.gov/pubmed/36187797
http://dx.doi.org/10.3389/fphys.2022.983506