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Defining and targeting patterns of T cell dysfunction in inborn errors of immunity

Inborn errors of immunity (IEIs) are a group of more than 450 monogenic disorders that impair immune development and function. A subset of IEIs blend increased susceptibility to infection, autoimmunity, and malignancy and are known collectively as primary immune regulatory disorders (PIRDs). While m...

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Detalles Bibliográficos
Autores principales: Campos, Jose S., Henrickson, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516113/
https://www.ncbi.nlm.nih.gov/pubmed/36189259
http://dx.doi.org/10.3389/fimmu.2022.932715