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Kir6.1/K-ATP channel in astrocytes is an essential negative modulator of astrocytic pyroptosis in mouse model of depression

Rationale: Astrocyte dysfunction is one of the important pathological mechanisms of depression. Stress contributes to the onset of depression. As metabolic stress sensor, Kir6.1-contaning K-ATP channel (Kir6.1/K-ATP) is prominently expressed in astrocytes. However, the involvement of Kir6.1/K-ATP ch...

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Detalles Bibliográficos
Autores principales: Li, Feng, Jiang, Si-Yuan, Tian, Tian, Li, Wen-Jie, Xue, You, Du, Ren-Hong, Hu, Gang, Lu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516231/
https://www.ncbi.nlm.nih.gov/pubmed/36185602
http://dx.doi.org/10.7150/thno.77455