Cargando…

Kir6.1/K-ATP channel in astrocytes is an essential negative modulator of astrocytic pyroptosis in mouse model of depression

Rationale: Astrocyte dysfunction is one of the important pathological mechanisms of depression. Stress contributes to the onset of depression. As metabolic stress sensor, Kir6.1-contaning K-ATP channel (Kir6.1/K-ATP) is prominently expressed in astrocytes. However, the involvement of Kir6.1/K-ATP ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Feng, Jiang, Si-Yuan, Tian, Tian, Li, Wen-Jie, Xue, You, Du, Ren-Hong, Hu, Gang, Lu, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516231/ https://www.ncbi.nlm.nih.gov/pubmed/36185602 http://dx.doi.org/10.7150/thno.77455

Ejemplares similares

Kir6.1/K-ATP channel modulates microglia phenotypes: implication in Parkinson’s disease
por: Du, Ren-Hong, et al.
Publicado: (2018)

Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the K(ATP) channel
por: Remedi, Maria S., et al.
Publicado: (2017)

The pore-forming subunit Kir6.1 of the K-ATP channel negatively regulates the NLRP3 inflammasome to control insulin resistance by interacting with NLRP3
por: Du, Ren-Hong, et al.
Publicado: (2019)

Astrocytic Kir4.1 channels and gap junctions account for spontaneous epileptic seizure
por: Du, Mengmeng, et al.
Publicado: (2018)

Role of Astrocytic Inwardly Rectifying Potassium (Kir) 4.1 Channels in Epileptogenesis
por: Kinboshi, Masato, et al.
Publicado: (2020)

Emerging Roles of Astrocyte Kir4.1 Channels in the Pathogenesis and Treatment of Brain Diseases
por: Ohno, Yukihiro, et al.
Publicado: (2021)

K(ATP) Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia
por: Li, Hong, et al.
Publicado: (2021)

Regulation of Kir4.1 expression in astrocytes and astrocytic tumors: a role for interleukin-1 β
por: Zurolo, Emanuele, et al.
Publicado: (2012)

Opening of Astrocytic Mitochondrial ATP-Sensitive Potassium Channels Upregulates Electrical Coupling between Hippocampal Astrocytes in Rat Brain Slices
por: Wang, Jiangping, et al.
Publicado: (2013)

Electroacupuncture prevents astrocyte atrophy to alleviate depression
por: Lin, Si-Si, et al.
Publicado: (2023)

Kir6.2-containing ATP-sensitive K(+) channel is required for cardioprotection of resveratrol in mice
por: Du, Ren-Hong, et al.
Publicado: (2014)

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy
por: Sicca, Federico, et al.
Publicado: (2016)

Astrocytic Kir4.1 potassium channels as a novel therapeutic target for epilepsy and mood disorders
por: Ohno, Yukihiro
Publicado: (2018)

Inwardly Rectifying Potassium Channel Kir4.1 as a Novel Modulator of BDNF Expression in Astrocytes
por: Ohno, Yukihiro, et al.
Publicado: (2018)

New Insights into GFAP Negative Astrocytes in Calbindin D28k Immunoreactive Astrocytes
por: Xu, Jie
Publicado: (2018)

Unconjugated bilirubin induces pyroptosis in cultured rat cortical astrocytes
por: Feng, Jie, et al.
Publicado: (2018)

Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in K(ATP) channels
por: Pratt, Emily B., et al.
Publicado: (2012)

Control of Rectification and Gating of Cloned K(ATP) Channels by the Kir6.2 Subunit
por: Shyng, S.-L., et al.
Publicado: (1997)

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice
por: Tong, Xiaoping, et al.
Publicado: (2014)

Expressional analysis of the astrocytic Kir4.1 channel in a pilocarpine–induced temporal lobe epilepsy model
por: Nagao, Yuki, et al.
Publicado: (2013)

Kir6.1- and SUR2-dependent K(ATP) overactivity disrupts intestinal motility in murine models of Cantú syndrome
por: York, Nathaniel W., et al.
Publicado: (2020)

Zoledronic Acid as a Novel Dual Blocker of KIR6.1/2-SUR2 Subunits of ATP-Sensitive K(+) Channels: Role in the Adverse Drug Reactions
por: Maqoud, Fatima, et al.
Publicado: (2021)

Zoledronic Acid Blocks Overactive Kir6.1/SUR2-Dependent K(ATP) Channels in Skeletal Muscle and Osteoblasts in a Murine Model of Cantú Syndrome
por: Scala, Rosa, et al.
Publicado: (2023)

Diacylglycerol Signaling Underlies Astrocytic ATP Release
por: Mungenast, Alison E.
Publicado: (2011)

Oxygen-glucose deprivation induces ATP release via maxi-anion channels in astrocytes
por: Liu, Hong-Tao, et al.
Publicado: (2007)

Downregulation of Astrocytic Kir4.1 Potassium Channels Is Associated with Hippocampal Neuronal Hyperexcitability in Type 2 Diabetic Mice
por: Méndez-González, Miguel P., et al.
Publicado: (2020)

Sulfonylurea and K(+)-Channel Opener Sensitivity of K(ATP) Channels: Functional Coupling of Kir6.2 and Sur1 Subunits
por: Koster, J.C., et al.
Publicado: (1999)

Antiepileptic Drugs Elevate Astrocytic Kir4.1 Expression in the Rat Limbic Region
por: Mukai, Takahiro, et al.
Publicado: (2018)

Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes
por: Kinboshi, Masato, et al.
Publicado: (2017)

ATP and potassium ions: a deadly combination for astrocytes
por: Jackson, David G., et al.
Publicado: (2014)

Glioactive ATP controls BDNF recycling in cortical astrocytes
por: Vignoli, Beatrice, et al.
Publicado: (2017)

Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K(+) channels
por: Heitz, Benjamin A., et al.
Publicado: (2021)

Inflammasome-Induced Osmotic Pressure and the Mechanical Mechanisms Underlying Astrocytic Swelling and Membrane Blebbing in Pyroptosis
por: Zheng, Zihui, et al.
Publicado: (2021)

EMMPRIN Is an Independent Negative Prognostic Factor for Patients with Astrocytic Glioma
por: Tian, Li, et al.
Publicado: (2013)

Involvement of SUR2/Kir6.1 channel in the physiopathology of pulmonary arterial hypertension
por: Le Ribeuz, Hélène, et al.
Publicado: (2023)

From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel
por: Trezza, Alfonso, et al.
Publicado: (2018)

NLRP3/caspase-1/GSDMD–mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression
por: Li, Shanshan, et al.
Publicado: (2021)

Neuromodulation of Astrocytic K(+) Clearance
por: Bellot-Saez, Alba, et al.
Publicado: (2021)

Kir4.1 is coexpressed with stemness markers in activated astrocytes in the injured brain and a Kir4.1 inhibitor BaCl(2) negatively regulates neurosphere formation in culture
por: Kwon, Jae-Kyung, et al.
Publicado: (2021)

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength
por: Kelley, Kevin W., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nt9spd0lmi2rec8lgqeenq7hjl