TEM8 Tri-specific Killer Engager binds both tumor and tumor stroma to specifically engage natural killer cell anti-tumor activity

BACKGROUND: The tumor microenvironment contains stromal cells, including endothelial cells and fibroblasts, that aid tumor growth and impair immune cell function. Many solid tumors remain difficult to cure because of tumor-promoting stromal cells, but current therapies targeting tumor stromal cells...

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Detalles Bibliográficos
Autores principales: Kaminski, Michael F, Bendzick, Laura, Hopps, Rachel, Kauffman, Marissa, Kodal, Behiye, Soignier, Yvette, Hinderlie, Peter, Walker, Joshua T, Lenvik, Todd R, Geller, Melissa A, Miller, Jeffrey S, Felices, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516302/
https://www.ncbi.nlm.nih.gov/pubmed/36162918
http://dx.doi.org/10.1136/jitc-2022-004725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516302/
https://www.ncbi.nlm.nih.gov/pubmed/36162918
http://dx.doi.org/10.1136/jitc-2022-004725

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