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Exploring differential exon usage via short- and long-read RNA sequencing strategies

Alternative splicing produces various mRNAs, and thereby various protein products, from one gene, impacting a wide range of cellular activities. However, accurate reconstruction and quantification of full-length transcripts using short-reads is limited, due to their length. Long-reads sequencing tec...

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Detalles Bibliográficos
Autores principales: Leshkowitz, Dena, Kedmi, Merav, Fried, Yael, Pilzer, David, Keren-Shaul, Hadas, Ainbinder, Elena, Dassa, Bareket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516339/
https://www.ncbi.nlm.nih.gov/pubmed/36168804
http://dx.doi.org/10.1098/rsob.220206