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Binding properties of the anti-TB drugs bedaquiline and TBAJ-876 to a mycobacterial F-ATP synthase

Tuberculosis (TB), the deadly disease caused by Mycobacterium tuberculosis (Mtb), kills more people worldwide than any other bacterial infectious disease. There has been a recent resurgence of TB drug discovery activities, resulting in the identification of a number of novel enzyme inhibitors. Many...

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Detalles Bibliográficos
Autores principales: Krah, Alexander, Grüber, Gerhard, Bond, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516385/
https://www.ncbi.nlm.nih.gov/pubmed/36186842
http://dx.doi.org/10.1016/j.crstbi.2022.09.001