Microarchitectural mimicking of stroma-induced vasculature compression in pancreatic tumors using a 3D engineered model

Fibrotic tumors, such as pancreatic ductal adenocarcinoma (PDAC), are characterized for high desmoplastic reaction, which results in high intra-tumoral solid stress leading to the compression of blood vessels. These microarchitectural alterations cause loss of blood flow and poor intra-tumoral deliv...

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Detalles Bibliográficos
Autores principales: Heinrich, Marcel Alexander, Uboldi, Irene, Kuninty, Praneeth Reddy, Ankone, Marc J.K., van Baarlen, Joop, Zhang, Yu Shrike, Jain, Kartik, Prakash, Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516389/
https://www.ncbi.nlm.nih.gov/pubmed/36203956
http://dx.doi.org/10.1016/j.bioactmat.2022.09.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516389/
https://www.ncbi.nlm.nih.gov/pubmed/36203956
http://dx.doi.org/10.1016/j.bioactmat.2022.09.015

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