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Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging
The early B cell protein λ5 is an essential component of the surrogate light chain and the preB cell receptor (preBCR), which is critical for optimal B cell development. To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J(H) (-/-) , λ5(-/-), J(H) (...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516392/ https://www.ncbi.nlm.nih.gov/pubmed/36189270 http://dx.doi.org/10.3389/fimmu.2022.906649 |