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Effect of X-ray radiation on the pharmacokinetics of apatinib in vivo in rats

Purpose: The “radiotherapy-pharmacokinetic” (“RT-PK”) phenomenon refers to the fact that radiation can significantly alter the pharmacokinetic behavior of a drug. At present, it is not clear whether there is an “RT-PK” phenomenon that can affect apatinib during concurrent chemoradiotherapy. In this...

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Detalles Bibliográficos
Autores principales: Dong, Shi-Qi, Yang, Fan, Zhang, Dong-Xu, Wang, Ling-Mei, Liu, Jian-Feng, Zhang, Ai-Jie, Fan, Hui-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516395/
https://www.ncbi.nlm.nih.gov/pubmed/36188594
http://dx.doi.org/10.3389/fphar.2022.943812