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Isoginkgetin, a bioactive constituent from Ginkgo Biloba, protects against obesity-induced cardiomyopathy via enhancing Nrf2/ARE signaling

Obesity-induced metabolic cardiomyopathy (MC), characterized by lipotoxicity and excessive oxidative stress, emerges as the leading cause of heart failure in the obese patients. Yet, its therapy remains very limited. Here, we demonstrated that isoginkgetin (IGK), a bioactive biflavonoid isolated fro...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoqian, Huang, Jianrong, Tang, Junyuan, Sun, Yuling, Zhao, Guojun, Yan, Cuishi, Liu, Zhenghong, Yi, Wei, Xu, Suowen, Yu, Xiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516449/
https://www.ncbi.nlm.nih.gov/pubmed/36162256
http://dx.doi.org/10.1016/j.redox.2022.102485