Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells

Residual cancer cells that survive upfront drug treatments act as a reservoir from which eventual resistant disease emerges. Although there is great interest in therapeutically targeting residual cells, efforts to do so are hampered by our limited knowledge of the vulnerabilities existing in this ce...

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Detalles Bibliográficos
Autores principales: Ali, Moiez, Lu, Min, Ang, Hazel Xiaohui, Soderquist, Ryan S., Eyler, Christine E., Hutchinson, Haley M., Glass, Carolyn, Bassil, Christopher F., Lopez, Omar M., Kerr, D. Lucas, Falcon, Christina J., Yu, Helena A., Hata, Aaron N., Blakely, Collin M., McCoach, Caroline E., Bivona, Trever G., Wood, Kris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516479/
https://www.ncbi.nlm.nih.gov/pubmed/35353542
http://dx.doi.org/10.1126/scitranslmed.abc7480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516479/
https://www.ncbi.nlm.nih.gov/pubmed/35353542
http://dx.doi.org/10.1126/scitranslmed.abc7480

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