A genetically encoded BRET-based SARS-CoV-2 M(pro) protease activity sensor

The main protease, M(pro), is critical for SARS-CoV-2 replication and an appealing target for designing anti-SARS-CoV-2 agents. Therefore, there is a demand for the development of improved sensors to monitor its activity. Here, we report a pair of genetically encoded, bioluminescence resonance energ...

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Detalles Bibliográficos
Autores principales: Geethakumari, Anupriya M., Ahmed, Wesam S., Rasool, Saad, Fatima, Asma, Nasir Uddin, S. M., Aouida, Mustapha, Biswas, Kabir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516532/
https://www.ncbi.nlm.nih.gov/pubmed/36187754
http://dx.doi.org/10.1038/s42004-022-00731-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516532/
https://www.ncbi.nlm.nih.gov/pubmed/36187754
http://dx.doi.org/10.1038/s42004-022-00731-2

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