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Can Second Coordination Sphere and Long-Range Interactions Modulate Hydrogen Atom Transfer in a Non-Heme Fe(II)-Dependent Histone Demethylase?

[Image: see text] Fe(II)-dependent oxygenases employ hydrogen atom transfer (HAT) to produce a myriad of products. Understanding how such enzymes use dynamic processes beyond the immediate vicinity of the active site to control the selectivity and efficiency of HAT is important for metalloenzyme eng...

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Detalles Bibliográficos
Autores principales: Chaturvedi, Shobhit S., Jaber Sathik Rifayee, Simahudeen Bathir, Waheed, Sodiq O., Wildey, Jon, Warner, Cait, Schofield, Christopher J., Karabencheva-Christova, Tatyana G., Christov, Christo Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516565/
https://www.ncbi.nlm.nih.gov/pubmed/36186565
http://dx.doi.org/10.1021/jacsau.2c00345