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Liquid biopsy to detect resistance mutations against anti-epidermal growth factor receptor therapy in metastatic colorectal cancer

Colorectal cancer (CRC) is a major cause of mortality worldwide, associated with a steadily growing prevalence. Notably, the identification of KRAS, NRAS, and BRAF mutations has markedly improved targeted CRC therapy by affording treatments directed against the epidermal growth factor receptor (EGFR...

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Detalles Bibliográficos
Autores principales: Valenzuela, Guillermo, Burotto, Mauricio, Marcelain, Katherine, González-Montero, Jaime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516650/
https://www.ncbi.nlm.nih.gov/pubmed/36187383
http://dx.doi.org/10.4251/wjgo.v14.i9.1654