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Epigenetic features drastically impact CRISPR–Cas9 efficacy in plants

CRISPR–Cas9-mediated genome editing has been widely adopted for basic and applied biological research in eukaryotic systems. While many studies consider DNA sequences of CRISPR target sites as the primary determinant for CRISPR mutagenesis efficiency and mutation profiles, increasing evidence reveal...

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Detalles Bibliográficos
Autores principales: Weiss, Trevor, Crisp, Peter A, Rai, Krishan M, Song, Meredith, Springer, Nathan M, Zhang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516779/
https://www.ncbi.nlm.nih.gov/pubmed/35689624
http://dx.doi.org/10.1093/plphys/kiac285