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In vivo 3D profiling of site-specific human cancer cell morphotypes in zebrafish

Tissue microenvironments affect the functional states of cancer cells, but determining these influences in vivo has remained a challenge. We present a quantitative high-resolution imaging assay of single cancer cells in zebrafish xenografts to probe functional adaptation to variable cell-extrinsic c...

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Detalles Bibliográficos
Autores principales: Segal, Dagan, Mazloom-Farsibaf, Hanieh, Chang, Bo-Jui, Roudot, Philippe, Rajendran, Divya, Daetwyler, Stephan, Fiolka, Reto, Warren, Mikako, Amatruda, James F., Danuser, Gaudenz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9516844/
https://www.ncbi.nlm.nih.gov/pubmed/36155740
http://dx.doi.org/10.1083/jcb.202109100