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The influence of degree of labelling upon cellular internalisation of antibody-cell penetrating peptide conjugates
Antibody-based agents are increasingly used as therapeutics and imaging agents, yet are generally restricted to cell surface targets due to inefficient cellular internalisation and endosomal entrapment. Enhanced cell membrane translocation of antibodies can be achieved by the covalent attachment of...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517169/ https://www.ncbi.nlm.nih.gov/pubmed/36320284 http://dx.doi.org/10.1039/d2ra05274a |