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The EDN1 Missense Variant rs5370G > T Regulates Adaptation and Maladaptation under Hypobaric Hypoxia

Endothelin 1 (EDN1) encodes a potent endogenous vasoconstrictor, ET1, to maintain vascular homeostasis and redistribution of tissue blood flow during exercise. One of the EDN1 missense polymorphisms, rs5370 G/T, has strongly been associated with cardiopulmonary diseases. This study investigated the...

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Detalles Bibliográficos
Autores principales: Palmo, Tsering, Abbasi, Bilal Ahmed, Chanana, Neha, Sharma, Kavita, Faruq, Mohammed, Thinlas, Tashi, Abdin, Malik Z., Pasha, Qadar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517604/
https://www.ncbi.nlm.nih.gov/pubmed/36141455
http://dx.doi.org/10.3390/ijerph191811174