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Ineffectiveness of Antiresorptive Agent Drug Holidays in Osteoporosis Patients for Treatment of Medication-Related Osteonecrosis of the Jaw: Consideration from Immunohistological Observation of Osteoclast Suppression and Treatment Outcomes

In patients with osteoporosis receiving antiresorptive agents (ARs), it has been widely practiced to withdraw ARs for several months before tooth extraction and during treatment if medication-related osteonecrosis of the jaw (MRONJ) develops. This study examined the effects of drug holidays on recov...

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Detalles Bibliográficos
Autores principales: Omori, Keisuke, Otsuru, Mitsunobu, Morishita, Kota, Hayashida, Saki, Suyama, Koki, Naruse, Tomofumi, Soutome, Sakiko, Umeda, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9517825/
https://www.ncbi.nlm.nih.gov/pubmed/36078614
http://dx.doi.org/10.3390/ijerph191710898