Synthesis and structure–activity relationships for some novel diflapolin derivatives with benzimidazole subunit

A series of derivatives of the potent dual soluble epoxide hydrolase (sEH)/5-lipoxygenase-activating protein (FLAP) inhibitor diflapolin was designed, synthesised, and characterised. These novel compounds, which contain a benzimidazole subunit were evaluated for their inhibitory activity against sEH...

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Detalles Bibliográficos
Autores principales: Vieider, Lisa, Zoeller, Eva, Romp, Erik, Schoenthaler, Martin, Hernández-Olmos, Victor, Temml, Veronika, Hasenoehrl, Thomas, Schuster, Daniela, Werz, Oliver, Garscha, Ulrike, Matuszczak, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518245/
https://www.ncbi.nlm.nih.gov/pubmed/36124840
http://dx.doi.org/10.1080/14756366.2022.2087645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518245/
https://www.ncbi.nlm.nih.gov/pubmed/36124840
http://dx.doi.org/10.1080/14756366.2022.2087645

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