Inhibition of Toxoplasma gondii by 1,2,4-triazole-based compounds: marked improvement in selectivity relative to the standard therapy pyrimethamine and sulfadiazine

A safer treatment for toxoplasmosis would be achieved by improving the selectivity profile of novel chemotherapeutics compared to the standard therapy pyrimethamine (PYR) and sulfadiazine (SDZ). We previously reported on the identification of the compounds with imidazole-thiosemicarbazide scaffold a...

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Detalles Bibliográficos
Autores principales: Węglińska, Lidia, Bekier, Adrian, Trotsko, Nazar, Kaproń, Barbara, Plech, Tomasz, Dzitko, Katarzyna, Paneth, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518248/
https://www.ncbi.nlm.nih.gov/pubmed/36165032
http://dx.doi.org/10.1080/14756366.2022.2112576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518248/
https://www.ncbi.nlm.nih.gov/pubmed/36165032
http://dx.doi.org/10.1080/14756366.2022.2112576

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